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Menopause & Hormone Health

Estradiol Vaginal Cream 0.01%

Localized estrogen therapy for eligible women experiencing vaginal and vulvar symptoms related to menopause.

RxPrescription treatment. Eligibility determined by a licensed clinician.

Pricing determined by treatment plan

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Good for
Vaginal Dryness
Local estrogen may help restore estrogen-responsive vaginal tissue.
Vaginal Discomfort
May help address menopause-related irritation and discomfort.
Pain With Intimacy
Can be prescribed for certain symptoms associated with vulvovaginal estrogen deficiency.
Local Hormone Support
Designed to deliver estrogen directly to vaginal tissues.
Menopause Care
An established local treatment option for appropriate patients.
Treatment type

Vaginal estrogen cream.

Prescription

Prescription medication provided if clinically approved.

A woman relaxing at home

Targeted support where it’s needed.

As estrogen levels decline during menopause, vaginal and vulvar tissues can become thinner, drier, and more sensitive.

Local estradiol therapy delivers estrogen directly to these tissues as part of clinician-guided menopause care.

Benefits

Vaginal estrogen can improve certain symptoms associated with vulvovaginal changes during menopause, including dryness and discomfort.

Your clinician will determine whether local estrogen therapy is appropriate for your symptoms and medical history.

How to use

Use estradiol vaginal cream exactly as prescribed.

Your treatment instructions will specify the amount, application method, frequency, and whether your schedule changes after the initial treatment period.

THE SCIENCE

Localized estrogen support.

Estrogen receptors are present throughout vaginal and vulvar tissues.

Declining estrogen levels can lead to changes in tissue thickness, moisture, elasticity, and comfort. Local estradiol acts directly on estrogen-responsive tissue.

WHAT IT MAY SUPPORT

Comfort through hormonal change.

01

Vaginal Dryness

Helps address menopause-related dryness.

02

Tissue Health

Supports estrogen-responsive vaginal tissue.

03

Intimate Comfort

May reduce certain menopause-related discomfort.

04

Localized Care

Delivers estrogen directly to the treatment area.

Individual results may vary. Estradiol vaginal cream is available by prescription only, when a licensed clinician determines it is appropriate for you. This information is not medical advice.

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HOW IT WORKS

Your wellness journey, made simple

Expert care, personalized for you, in five easy steps.

  1. 01.

    COMPLETE A SHORT INTAKE

    Answer a few quick questions so we can understand your wellness goals and help guide your bundle.

  2. 02.

    BUILD YOUR BUNDLE

    Choose the products that fit your needs, with flexible monthly or quarterly options designed around your routine.

  3. 03.

    A LICENSED PROVIDER REVIEWS

    A licensed medical provider reviews your answers to determine whether your selected treatment plan is appropriate for you.

  4. 04.

    GET YOUR PERSONALIZED PLAN

    If approved, you’ll receive a personalized treatment plan tailored to your selected bundle and wellness goals.

  5. 05.

    SHIPPED FROM THE PHARMACY

    Your treatments are shipped directly from the pharmacy in their own packaging, so you receive your order quickly and discreetly.

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FREQUENTLY ASKED QUESTIONS

Good to know

Doctor consult included. Free shipping. Cancel anytime.

How does VIVIE work?

Choose the treatment or bundle that fits your goals, create your account, and complete a short medical intake. A licensed provider reviews your information and, if clinically appropriate, issues your prescription. Your treatment is then fulfilled and shipped directly by a licensed pharmacy.

Do I need a prescription?

Yes. Prescription treatments available through VIVIE require review and approval by a licensed healthcare provider. Completing the intake or selecting a treatment does not guarantee a prescription.

What if a provider decides a treatment isn’t right for me?

Your provider will only prescribe a treatment they determine is medically appropriate for you. If your selected treatment isn’t a good fit, they may recommend another option, request additional information, or advise you on next steps.

If your treatment is not approved, you will not be charged. Any payment authorization placed on hold will be released back to your account.

Can I talk to a medical provider?

Yes. You have access to your provider through secure doctor chat in your patient portal.

How quickly will I feel a difference?

It depends on the treatment and your individual response. Some people may notice changes sooner than others, while certain treatments may take more time and consistent use.

Is my information private?

Yes. VIVIE takes the privacy and security of your personal and health information seriously. Your information is handled in accordance with applicable privacy and healthcare laws and is only shared as necessary to provide your care and services.

You can learn more in our Privacy Policy.

Can I cancel or change my treatment?

Yes. You can request to cancel or change your treatment through your patient portal or by contacting us.

Treatment changes require provider approval. Once a prescription has entered pharmacy fulfillment, we cannot guarantee that the current order can be changed, canceled, or refunded.

Who is the medical provider?

Our clinical provider is Wasef Health, PC, led by Michael Wasef, MD.

Email: contact@wasef-health.com
Address: 5260 78th Ave N, PO Box 1697, Pinellas Park, FL 33780

Which pharmacy fulfills my medication?

Our pharmacy partner is VialsRx.

Phone: (713) 497-5590
Address: 6220 Westpark Dr., Houston, TX 77057
Website: vials.ai

Services are available through affiliated medical providers and pharmacy partners operating in accordance with applicable state licensure requirements. Medication availability, formulations, and fulfillment options may vary depending on your location and applicable state pharmacy regulations.

Doctor Consult Included . Free Shipping . Cancel Anytime

Estradiol Vaginal Cream 0.01%

Rx only · Clinician approval required

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